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Insulin resistance occurs when cells in your muscles, fat, and liver don’t respond well to insulin and can’t easily take up glucose from your blood. As a result, your pancreas makes more insulin to help glucose enter your cells.

Causes of insulin resistance include:

• Obesity, particularly excess fat around the abdomen
• Physical inactivity
• Genetic factors and family history
• Certain health conditions such as polycystic ovary syndrome (PCOS) or non-alcoholic fatty liver disease
• Poor diet high in refined carbohydrates and sugars

Insulin resistance is a key factor in the development of type 2 diabetes and is also linked to heart disease and metabolic syndrome. Managing insulin resistance typically involves lifestyle changes such as:

1. Adopting a healthy, balanced diet rich in whole foods
2. Increasing physical activity and exercise
3. Losing excess weight
4. Medications, if prescribed by a healthcare provider

Early detection and management are important to prevent complications associated with insulin resistance.

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